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Structure paper

TitleARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 29, Page 67-77, Year 2022
Publish dateDec 9, 2020 (structure data deposition date)
AuthorsXu, Y. / Cheng, S. / Zeng, H. / Zhou, P. / Ma, Y. / Li, L. / Liu, X. / Shao, F. / Ding, J.
External linksNat. Struct. Mol. Biol. / PubMed:35046574
MethodsX-ray diffraction
Resolution2.6084 - 3.29 Å
Structure data

PDB-7dn8:
Crystal structure of Salmonella effector SopF in complex with ARF1
Method: X-RAY DIFFRACTION / Resolution: 2.6084 Å

PDB-7dn9:
Crystal structure of Salmonella effector in complex with NAD and host co-factor ARF1
Method: X-RAY DIFFRACTION / Resolution: 3.29 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

Source
  • salmonella typhimurium (strain lt2 / sgsc1412 / atcc 700720) (bacteria)
  • homo sapiens (human)
KeywordsTRANSFERASE / ADP-ribosyltransferase

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