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TitleComputational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants.
Journal, issue, pagesMabs, Vol. 14, Page 2021601-2021601, Year 2022
Publish dateNov 15, 2021 (structure data deposition date)
AuthorsJeong, B.S. / Cha, J.S. / Hwang, I. / Kim, U. / Adolf-Bryfogle, J. / Coventry, B. / Cho, H.S. / Kim, K.D. / Oh, B.H.
External linksMabs / PubMed:35030983
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-7vyr:
Crystal structure of SARS-CoV-2 Spike RBD in complex with the D27 neutralizing antibody Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Computational design / Neutralizing antibody / SARS-CoV-2 / VIRAL PROTEIN / IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM complex

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