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-Structure paper
Title | A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells. |
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Journal, issue, pages | Commun Biol, Vol. 4, Page 1420-1420, Year 2021 |
Publish date | Nov 18, 2019 (structure data deposition date) |
![]() | Li, J. / Garavaglia, S. / Ye, Z. / Moretti, A. / Belyaeva, O.V. / Beiser, A. / Ibrahim, M. / Wilk, A. / McClellan, S. / Klyuyeva, A.V. ...Li, J. / Garavaglia, S. / Ye, Z. / Moretti, A. / Belyaeva, O.V. / Beiser, A. / Ibrahim, M. / Wilk, A. / McClellan, S. / Klyuyeva, A.V. / Goggans, K.R. / Kedishvili, N.Y. / Salter, E.A. / Wierzbicki, A. / Migaud, M.E. / Mullett, S.J. / Yates, N.A. / Camacho, C.J. / Rizzi, M. / Sobol, R.W. |
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Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | ![]() PDB-6tgw: |
Chemicals | ![]() ChemComp-NAD: ![]() ChemComp-N98: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / ALDH1A3 / aldehyde dehydrogenase ALDH inhibitor Cancer stem cell / glioblastoma mesenchymal stem cell stem cell |