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TitleThe molecular basis for the development of adult T-cell leukemia/lymphoma in patients with an IRF4 K59R mutation.
Journal, issue, pagesProtein Sci., Vol. 31, Page 787-796, Year 2022
Publish dateJul 16, 2021 (structure data deposition date)
AuthorsSundararaj, S. / Seneviratne, S. / Williams, S.J. / Enders, A. / Casarotto, M.G.
External linksProtein Sci. / PubMed:34913532
MethodsX-ray diffraction
Resolution2.47 Å
Structure data

PDB-7rh2:
IRF4 Transcription factor mutant -K59R
Method: X-RAY DIFFRACTION / Resolution: 2.47 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / IRF4 / Cancer / Homodimer complex / protein/DNA interaction / Transcription factor

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