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-Structure paper
Title | Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities. |
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Journal, issue, pages | Biorxiv, Year 2021 |
Publish date | Aug 4, 2021 (structure data deposition date) |
![]() | Chen, Y. / Sun, L. / Ullah, I. / Beaudoin-Bussieres, G. / Anand, S.P. / Hederman, A.P. / Tolbert, W.D. / Sherburn, R. / Nguyen, D.N. / Marchitto, L. ...Chen, Y. / Sun, L. / Ullah, I. / Beaudoin-Bussieres, G. / Anand, S.P. / Hederman, A.P. / Tolbert, W.D. / Sherburn, R. / Nguyen, D.N. / Marchitto, L. / Ding, S. / Wu, D. / Luo, Y. / Gottumukkala, S. / Moran, S. / Kumar, P. / Piszczek, G. / Mothes, W. / Ackerman, M.E. / Finzi, A. / Uchil, P.D. / Gonzalez, F.J. / Pazgier, M. |
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Methods | X-ray diffraction |
Resolution | 3.54 Å |
Structure data | ![]() PDB-7rpv: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-ZN: ![]() ChemComp-HOH: |
Source |
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![]() | Hydrolase/Viral protein / SARS-CoV-2 / receptor binding domain / engineered human ACE2 / enhanced affinity / catalytic-null / zinc binding site / Hydrolase-Viral protein complex |