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TitleCrystal structure of the Propionibacterium acnes surface sialidase, a drug target for P. acnes-associated diseases.
Journal, issue, pagesGlycobiology, Vol. 32, Page 162-170, Year 2022
Publish dateJan 8, 2021 (structure data deposition date)
AuthorsYu, A.C.Y. / Volkers, G. / Jongkees, S.A.K. / Worrall, L.J. / Withers, S.G. / Strynadka, N.C.J.
External linksGlycobiology / PubMed:34792586
MethodsX-ray diffraction
Resolution1.7 - 2.11 Å
Structure data

PDB-7lbu:
Crystal structure of the Propionibacterium acnes surface sialidase
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

PDB-7lbv:
Crystal structure of the Propionibacterium acnes surface sialidase in complex with Neu5Ac2en
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-DAN:
2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID

Source
  • cutibacterium acnes (bacteria)
KeywordsHYDROLASE / acne

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