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-Structure paper
Title | Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 61, Page e202112295-e202112295, Year 2022 |
Publish date | Apr 26, 2021 (structure data deposition date) |
![]() | Kaya, C. / Walter, I. / Yahiaoui, S. / Sikandar, A. / Alhayek, A. / Konstantinovic, J. / Kany, A.M. / Haupenthal, J. / Kohnke, J. / Hartmann, R.W. / Hirsch, A.K.H. |
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Methods | X-ray diffraction |
Resolution | 1.95 Å |
Structure data | ![]() PDB-7oc7: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-V85: ![]() ChemComp-CA: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / LasB / alpha-alkyl-N-aryl mercaptoacetamide |