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-Structure paper
Title | A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins. |
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Journal, issue, pages | Biochem Pharmacol, Vol. 194, Page 114819-114819, Year 2021 |
Publish date | Jul 29, 2021 (structure data deposition date) |
Authors | Segawa, R. / Takeda, H. / Yokoyama, T. / Ishida, M. / Miyata, C. / Saito, T. / Ishihara, R. / Nakagita, T. / Sasano, Y. / Kanoh, N. ...Segawa, R. / Takeda, H. / Yokoyama, T. / Ishida, M. / Miyata, C. / Saito, T. / Ishihara, R. / Nakagita, T. / Sasano, Y. / Kanoh, N. / Iwabuchi, Y. / Mizuguchi, M. / Hiratsuka, M. / Hirasawa, N. |
External links | Biochem Pharmacol / PubMed:34757034 |
Methods | X-ray diffraction |
Resolution | 2.492 Å |
Structure data | PDB-7fh2: |
Chemicals | ChemComp-4JI: ChemComp-CL: ChemComp-HOH: |
Source |
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Keywords | TRANSCRIPTION / INHIBITOR / BROMODOMAIN / BRD4 / HISTONE |