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TitleCooperative stabilisation of 14-3-3 sigma protein-protein interactions via covalent protein modification.
Journal, issue, pagesChem Sci, Vol. 12, Page 12985-12992, Year 2021
Publish dateFeb 8, 2021 (structure data deposition date)
AuthorsFalcicchio, M. / Ward, J.A. / Chothia, S.Y. / Basran, J. / Mohindra, A. / Macip, S. / Roversi, P. / Doveston, R.G.
External linksChem Sci / PubMed:34745529
MethodsX-ray diffraction
Resolution1.19 - 1.48 Å
Structure data

PDB-7nfw:
Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

PDB-7niz:
Human 14-3-3 sigma in complex with human Estrogen Receptor alpha peptide and ligands Fusicoccin-A and WR-1065
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-FSC:
FUSICOCCIN

ChemComp-UGH:
WR-1065

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / SIGNALING PROTEIN-PEPTIDE complex / Fusicoccin-A / WR-1065

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