タイトル | Structure-based investigation of fluorogenic Pepper aptamer. |
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ジャーナル・号・ページ | Nat. Chem. Biol., Vol. 17, Page 1289-1295, Year 2021 |
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掲載日 | 2021年4月22日 (構造データの登録日) |
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著者 | Huang, K. / Chen, X. / Li, C. / Song, Q. / Li, H. / Zhu, L. / Yang, Y. / Ren, A. |
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リンク | Nat. Chem. Biol. / PubMed:34725509 |
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手法 | X線回折 |
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解像度 | 1.5 - 2.703 Å |
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構造データ | PDB-7eog: Crystal structure of the Pepper aptamer in complex with HBC, iridium hexammine soak 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-7eoh: Crystal structure of the Pepper aptamer in complex with HBC 手法: X-RAY DIFFRACTION / 解像度: 1.637 Å PDB-7eoi: Crystal structure of the Pepper aptamer in complex with HBC, manganese soak 手法: X-RAY DIFFRACTION / 解像度: 1.92 Å PDB-7eoj: Crystal structure of the Pepper aptamer in complex with HBC, cesium soak 手法: X-RAY DIFFRACTION / 解像度: 1.77 Å PDB-7eok: Crystal structure of the Pepper aptamer in complex with HBC485 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-7eol: Crystal structure of the Pepper aptamer in complex with HBC497 手法: X-RAY DIFFRACTION / 解像度: 2.309 Å PDB-7eom: Crystal structure of the Pepper aptamer in complex with HBC508 手法: X-RAY DIFFRACTION / 解像度: 2.703 Å PDB-7eon: Crystal structure of the Pepper aptamer in complex with HBC514 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-7eoo: Crystal structure of the Pepper aptamer in complex with HBC525 手法: X-RAY DIFFRACTION / 解像度: 2.23 Å PDB-7eop: Crystal structure of the Pepper aptamer in complex with HBC620 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å |
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化合物 | ChemComp-J8F: 4-[(~{Z})-1-cyano-2-[4-[2-hydroxyethyl(methyl)amino]phenyl]ethenyl]benzenecarbonitrile
ChemComp-J8L: 4-[(~{Z})-1-cyano-2-[5-[2-(dimethylamino)ethyl-methyl-amino]pyrazin-2-yl]ethenyl]benzenecarbonitrile
ChemComp-J8O: 4-[(~{Z})-1-cyano-2-[5-[2-hydroxyethyl(methyl)amino]pyrazin-2-yl]ethenyl]benzenecarbonitrile
ChemComp-J8R: 4-[(~{Z})-1-cyano-2-[6-[2-hydroxyethyl(methyl)amino]pyridin-3-yl]ethenyl]benzenecarbonitrile
ChemComp-J8U: 4-[(~{Z})-1-cyano-2-[4-[2-(dimethylamino)ethyl-methyl-amino]phenyl]ethenyl]benzenecarbonitrile
ChemComp-J8X: (~{E})-2-(1,3-benzoxazol-2-yl)-3-[4-[2-hydroxyethyl(methyl)amino]phenyl]prop-2-enenitrile
ChemComp-J93: 4-[(~{Z})-1-cyano-2-[5-[2-hydroxyethyl(methyl)amino]thieno[3,2-b]thiophen-2-yl]ethenyl]benzenecarbonitrile
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由来 | - synthetic construct (人工物)
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キーワード | RNA / Fluorescent RNA / Aptamer / HBC / HBC485 / HBC497 / HBC508 / HBC514 / HBC525 / HBC620 |
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