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TitleNeutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Journal, issue, pagesAdv Sci, Vol. 9, Page e2102181-e2102181, Year 2022
Publish dateNov 4, 2020 (structure data deposition date)
AuthorsQiang, M. / Ma, P. / Li, Y. / Liu, H. / Harding, A. / Min, C. / Wang, F. / Liu, L. / Yuan, M. / Ji, Q. ...Qiang, M. / Ma, P. / Li, Y. / Liu, H. / Harding, A. / Min, C. / Wang, F. / Liu, L. / Yuan, M. / Ji, Q. / Tao, P. / Shi, X. / Li, Z. / Li, T. / Wang, X. / Zhang, Y. / Wu, N.C. / Lee, C.D. / Zhu, X. / Gilbert-Jaramillo, J. / Zhang, C. / Saxena, A. / Huang, X. / Wang, H. / James, W. / Dwek, R.A. / Wilson, I.A. / Yang, G. / Lerner, R.A.
External linksAdv Sci / PubMed:34716683
MethodsX-ray diffraction
Resolution2.251 - 2.7 Å
Structure data

PDB-7kn3:
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.251 Å

PDB-7kn4:
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-E6 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / SARS-CoV-2 / Antibody / Spike / Coronavirus / COVID-19 / IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM complex / phage display / pre-pandemic

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