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TitleA cell permeable bimane-constrained PCNA-interacting peptide.
Journal, issue, pagesRsc Chem Biol, Vol. 2, Page 1499-1508, Year 2021
Publish dateMar 24, 2021 (structure data deposition date)
AuthorsHorsfall, A.J. / Vandborg, B.A. / Kikhtyak, Z. / Scanlon, D.B. / Tilley, W.D. / Hickey, T.E. / Bruning, J.B. / Abell, A.D.
External linksRsc Chem Biol / PubMed:34704055
MethodsX-ray diffraction
Resolution3 - 3.11 Å
Structure data

PDB-7m5l:
PCNA bound to peptide mimetic with linker
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-7m5m:
PCNA bound to peptide mimetic
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-7m5n:
PCNA bound to peptide mimetic with linker
Method: X-RAY DIFFRACTION / Resolution: 3.11 Å

Chemicals

ChemComp-TME:
PROPANE

ChemComp-NBU:
N-BUTANE

ChemComp-8VH:
1,3-dimethylbenzene

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsREPLICATION / PCNA / DNA replication / peptide mimetic

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