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Structure paper

TitleStructural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Journal, issue, pagesSci Adv, Vol. 7, Page eabi4582-eabi4582, Year 2021
Publish dateAug 31, 2021 (structure data deposition date)
AuthorsLiu, Z. / Zhang, S. / Chen, P. / Tian, S. / Zeng, J. / Perry, K. / Dong, M. / Jin, R.
External linksSci Adv / PubMed:34678063
MethodsX-ray diffraction
Resolution2.34 - 2.79 Å
Structure data

PDB-7s0y:
Structures of TcdB in complex with Cdc42
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

PDB-7s0z:
Structures of TcdB in complex with R-Ras
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-SO4:
SULFATE ION

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NH4:
AMMONIUM ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ACT:
ACETATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GLC:
alpha-D-glucopyranose

Source
  • clostridioides difficile (bacteria)
  • homo sapiens (human)
KeywordsHYDROLASE / toxin / substrate / enzyme / Hydrolase/Transferase / Hydrolase-Transferase complex

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