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TitleStructural analysis of the boronic acid beta-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3.
Journal, issue, pagesPlos One, Vol. 16, Page e0258359-e0258359, Year 2021
Publish dateMar 5, 2021 (structure data deposition date)
AuthorsKumar, V. / Viviani, S.L. / Ismail, J. / Agarwal, S. / Bonomo, R.A. / van den Akker, F.
External linksPlos One / PubMed:34653211
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-7ly1:
Crystal structure of Pseudomonas aeruginosa PBP3 in complex with vaborbactam
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-4D6:
Vaborbactam / antibiotic, inhibitor*YM

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / PBP3 / penicillin-binding protein / boronic acid inhibitor

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