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Structure paper

TitleReactions with Proteins of Three Novel Anticancer Platinum(II) Complexes Bearing N-Heterocyclic Ligands.
Journal, issue, pagesInt J Mol Sci, Vol. 22, Year 2021
Publish dateSep 7, 2021 (structure data deposition date)
AuthorsSacco, F. / Tarchi, M. / Ferraro, G. / Merlino, A. / Facchetti, G. / Rimoldi, I. / Messori, L. / Massai, L.
External linksInt J Mol Sci / PubMed:34638887
MethodsX-ray diffraction
Resolution1.22 - 2.13 Å
Structure data

PDB-7pnh:
X-ray structure of the adduct formed upon reaction of Pt(II) complex 2c with lysozyme
Method: X-RAY DIFFRACTION / Resolution: 1.22 Å

PDB-7pni:
X-ray structure of the adduct formed upon reaction of Pt(II) complex 2c with ribonuclease A
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-NO3:
NITRATE ION

ChemComp-PT:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-IMD:
IMIDAZOLE

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
  • bos taurus (domestic cattle)
KeywordsHYDROLASE / metallodrug / platinum / protein interaction / Pt-protein adduct / RNA BINDING PROTEIN

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