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-Structure paper
Title | Discovery and optimization of covalent EGFR T790M/L858R mutant inhibitors". |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Page 128406-128406, Year 2021 |
Publish date | Jun 22, 2021 (structure data deposition date) |
![]() | Hoogenboom, N. / Demont, D. / de Zwart, E. / Verkaik, S. / Emmelot, M. / van de Kar, B. / Kaptein, A. / Barf, T. |
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Methods | X-ray diffraction |
Resolution | 2.56 Å |
Structure data | ![]() PDB-7oxb: |
Chemicals | ![]() ChemComp-35Z: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Kinase / inhibitor / EGFR / mutant |