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TitleSynthesis and evaluation of peptidic thrombin inhibitors bearing acid-stable sulfotyrosine analogues.
Journal, issue, pagesChem. Commun. (Camb. ), Vol. 57, Page 10923-10926, Year 2021
Publish dateAug 18, 2021 (structure data deposition date)
AuthorsDowman, L.J. / Agten, S.M. / Ripoll-Rozada, J. / Calisto, B.M. / Pereira, P.J.B. / Payne, R.J.
External linksChem. Commun. (Camb. ) / PubMed:34596182
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-7phx:
Tsetse thrombin inhibitor in complex with human alpha-thrombin - acid-stable sulfotyrosine analogue
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • glossina morsitans morsitans (fry)
KeywordsBLOOD CLOTTING / anticoagulant; exosite II binding; sulfotyrosine sulfonate analogue

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