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-Structure paper
Title | Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen-Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 16, Page 2228-2243, Year 2021 |
Publish date | May 7, 2020 (structure data deposition date) |
![]() | Eron, S.J. / Huang, H. / Agafonov, R.V. / Fitzgerald, M.E. / Patel, J. / Michael, R.E. / Lee, T.D. / Hart, A.A. / Shaulsky, J. / Nasveschuk, C.G. ...Eron, S.J. / Huang, H. / Agafonov, R.V. / Fitzgerald, M.E. / Patel, J. / Michael, R.E. / Lee, T.D. / Hart, A.A. / Shaulsky, J. / Nasveschuk, C.G. / Phillips, A.J. / Fisher, S.L. / Good, A. |
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Methods | X-ray diffraction |
Resolution | 1.55 Å |
Structure data | ![]() PDB-6wvx: |
Chemicals | ![]() ChemComp-UDV: ![]() ChemComp-HOH: |
Source |
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![]() | GENE REGULATION/INHIBITOR / Inhibitor / bromodomain / BRD4 / benzodiazepine / GENE REGULATION / GENE REGULATION-INHIBITOR complex |