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Structure paper

TitleA Novel Antagonistic CD73 Antibody for Inhibition of the Immunosuppressive Adenosine Pathway.
Journal, issue, pagesMol. Cancer Ther., Vol. 20, Page 2250-2261, Year 2021
Publish dateDec 17, 2020 (structure data deposition date)
AuthorsWurm, M. / Schaaf, O. / Reutner, K. / Ganesan, R. / Mostbock, S. / Pelster, C. / Bottcher, J. / de Andrade Pereira, B. / Taubert, C. / Alt, I. ...Wurm, M. / Schaaf, O. / Reutner, K. / Ganesan, R. / Mostbock, S. / Pelster, C. / Bottcher, J. / de Andrade Pereira, B. / Taubert, C. / Alt, I. / Serna, G. / Auguste, A. / Stadermann, K.B. / Delic, D. / Han, F. / Capdevila, J. / Nuciforo, P.G. / Kroe-Barrett, R. / Adam, P.J. / Vogt, A.B. / Hofmann, I.
External linksMol. Cancer Ther. / PubMed:34482286
MethodsX-ray diffraction
Resolution2.72 Å
Structure data

PDB-7bbj:
CD73 in complex with the humanized antagonistic antibody mAb19
Method: X-RAY DIFFRACTION / Resolution: 2.72 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / antibody complex

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