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TitleTotal Synthesis of Tetrahydrolipstatin, Its Derivatives, and Evaluation of Their Ability to Potentiate Multiple Antibiotic Classes against Mycobacterium Species.
Journal, issue, pagesAcs Infect Dis., Vol. 7, Page 2876-2888, Year 2021
Publish dateMay 21, 2021 (structure data deposition date)
AuthorsKhan, S.S. / Sudasinghe, T.D. / Landgraf, A.D. / Ronning, D.R. / Sucheck, S.J.
External linksAcs Infect Dis. / PubMed:34478259
MethodsX-ray diffraction
Resolution2.51 Å
Structure data

PDB-7myg:
M. tb Ag85C modified by THL-10d
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTRANSFERASE / Mycolyltransferase / Alpha/Beta-hydrolase fold

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