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Structure paper

TitleBiophysical Investigation of Sodium Channel Interaction with beta-Subunit Variants Associated with Arrhythmias.
Journal, issue, pagesBioelectricity, Vol. 2, Page 269-278, Year 2020
Publish dateFeb 9, 2020 (structure data deposition date)
AuthorsLlongueras, J.P. / Das, S. / De Waele, J. / Capulzini, L. / Sorgente, A. / Van Petegem, F. / Bosmans, F.
External linksBioelectricity / PubMed:34476357
MethodsX-ray diffraction
Resolution1.45 - 1.62 Å
Structure data

PDB-6vrr:
Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-6vsv:
Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 4 subunit extracellular domain
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Sodium Channel / Beta sub-unit / SCN2B / Beta4 subunit / Disease mutant

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