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TitleStructural Characterization of a Macrocyclic Peptide Modulator of the PD-1/PD-L1 Immune Checkpoint Axis.
Journal, issue, pagesMolecules, Vol. 26, Year 2021
Publish dateJun 12, 2021 (structure data deposition date)
AuthorsZyla, E. / Musielak, B. / Holak, T.A. / Dubin, G.
External linksMolecules / PubMed:34443436
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-7oun:
Structure of human PD-L1 in complex with macrocyclic inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsCELL CYCLE / Programmed Death Ligand 1 / immune checkpoint inhibitor / cancer / IMMUNE SYSTEM

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