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TitleInsertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior.
Journal, issue, pagesBlood, Vol. 138, Page 1570-1582, Year 2021
Publish dateJun 16, 2020 (structure data deposition date)
AuthorsChiodin, G. / Allen, J.D. / Bryant, D.J. / Rock, P. / Martino, E.A. / Valle-Argos, B. / Duriez, P.J. / Watanabe, Y. / Henderson, I. / Blachly, J.S. ...Chiodin, G. / Allen, J.D. / Bryant, D.J. / Rock, P. / Martino, E.A. / Valle-Argos, B. / Duriez, P.J. / Watanabe, Y. / Henderson, I. / Blachly, J.S. / McCann, K.J. / Strefford, J.C. / Packham, G. / Geijtenbeek, T.B.H. / Figdor, C.G. / Wright, G.W. / Staudt, L.M. / Burack, R. / Bowden, T.A. / Crispin, M. / Stevenson, F.K. / Forconi, F.
External linksBlood / PubMed:34424958
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-6zec:
Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antibody / Fab / Glycosylated / Glycans / lymphoma

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