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TitleIdentification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Journal, issue, pagesAcs Chem. Biol., Vol. 16, Page 1745-1756, Year 2021
Publish dateMay 21, 2021 (structure data deposition date)
AuthorsMiddleton, A.J. / Teyra, J. / Zhu, J. / Sidhu, S.S. / Day, C.L.
External linksAcs Chem. Biol. / PubMed:34397214
MethodsX-ray diffraction
Resolution2.394 - 3 Å
Structure data

PDB-7myf:
Ubiquitin variant UbV.k.1 in complex with Ube2k
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-7myh:
Ubiquitin variant UbV.k.2 in complex with Ube2k
Method: X-RAY DIFFRACTION / Resolution: 2.394 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/INHIBITOR / Ubiquitin conjugating enzyme / degradation / ubiquitin variant / inhibitor / TRANSFERASE-INHIBITOR complex

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