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-Structure paper
Title | Structure of autoinhibited Akt1 reveals mechanism of PIP 3 -mediated activation. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 118, Year 2021 |
Publish date | Oct 16, 2020 (structure data deposition date) |
![]() | Truebestein, L. / Hornegger, H. / Anrather, D. / Hartl, M. / Fleming, K.D. / Stariha, J.T.B. / Pardon, E. / Steyaert, J. / Burke, J.E. / Leonard, T.A. |
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Methods | X-ray diffraction |
Resolution | 2.05 Å |
Structure data | ![]() PDB-7apj: |
Chemicals | ![]() ChemComp-HOH: |
Source |
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![]() | SIGNALING PROTEIN / kinase / autoinhibition / lipid / membrane / PIP3 / Akt |