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TitleStructural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein.
Journal, issue, pagesJ. Biol. Chem., Vol. 297, Page 101065-101065, Year 2021
Publish dateJun 8, 2021 (structure data deposition date)
AuthorsChaurasia, P. / Nguyen, T.H.O. / Rowntree, L.C. / Juno, J.A. / Wheatley, A.K. / Kent, S.J. / Kedzierska, K. / Rossjohn, J. / Petersen, J.
External linksJ. Biol. Chem. / PubMed:34384783
MethodsX-ray diffraction
Resolution2.3 - 3.2 Å
Structure data

PDB-7n6d:
HLA peptide complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-7n6e:
TCR peptide HLA-A2 complex
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsIMMUNE SYSTEM/VIRAL PROTEIN / peptide HLA complex / IMMUNE SYSTEM-VIRAL PROTEIN complex / T cell receptor / Human Leucocyte Antigen / SARS-CoV-2

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