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TitleCrystal Structure Reveals the Full Ras-Raf Interface and Advances Mechanistic Understanding of Raf Activation.
Journal, issue, pagesBiomolecules, Vol. 11, Year 2021
Publish dateJul 21, 2020 (structure data deposition date)
AuthorsCookis, T. / Mattos, C.
External linksBiomolecules / PubMed:34356620
MethodsX-ray diffraction
Resolution2.766 Å
Structure data

PDB-7jhp:
Crystal structure of HRas in complex with the Ras-binding and cysteine-rich domains of CRaf-kinase
Method: X-RAY DIFFRACTION / Resolution: 2.766 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Ras / Raf / RBD / CRD

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