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Structure paper

TitleStructure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons.
Journal, issue, pagesSci Rep, Vol. 11, Page 15663-15663, Year 2021
Publish dateJun 22, 2020 (structure data deposition date)
AuthorsMidgett, C.R. / Talbot, K.M. / Day, J.L. / Munson, G.P. / Kull, F.J.
External linksSci Rep / PubMed:34341412
MethodsX-ray diffraction
Resolution2.8 - 3 Å
Structure data

PDB-6xiu:
ETEC Rns bound to a potential inhibitor, decanoic acid
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6xiv:
SeMet-Rns, in complex with potential inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-DKA:
DECANOIC ACID

ChemComp-LMR:
(2S)-2-hydroxybutanedioic acid

Source
  • escherichia coli (E. coli)
KeywordsDNA BINDING PROTEIN/INHIBITOR / Inhibitor / AraC / ETEC / Virulence / transcription factor / DNA BINDING PROTEIN / DNA BINDING PROTEIN-INHIBITOR complex / Rns

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