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Structure paper

TitlePALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Journal, issue, pagesNat Commun, Vol. 12, Page 4592-4592, Year 2021
Publish dateNov 26, 2019 (structure data deposition date)
AuthorsZhang, Q. / Agius, S.C. / Flanigan, S.F. / Uckelmann, M. / Levina, V. / Owen, B.M. / Davidovich, C.
External linksNat Commun / PubMed:34321472
MethodsX-ray diffraction
Resolution1.63 - 1.7 Å
Structure data

PDB-6v3x:
Crystal structure of EED in complex with PALI1-K1241me3 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6v3y:
Crystal structure of EED in complex with PALI1-K1219me3 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / EED / PALI1 / LCOR / C10ORF12 / tri-methyl-lysine

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