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Structure paper

TitleDefining substrate selection by rhinoviral 2A proteinase through its crystal structure with the inhibitor zVAM.fmk.
Journal, issue, pagesVirology, Vol. 562, Page 128-141, Year 2021
Publish dateOct 23, 2020 (structure data deposition date)
AuthorsDeutschmann-Olek, K.M. / Yue, W.W. / Bezerra, G.A. / Skern, T.
External linksVirology / PubMed:34315103
MethodsX-ray diffraction
Resolution2.243 Å
Structure data

PDB-7ara:
Rhinovirus A2 2A protease in complex with zVAM.fmk
Method: X-RAY DIFFRACTION / Resolution: 2.243 Å

Chemicals

ChemComp-S7N:
(phenylmethyl) ~{N}-[(2~{R})-3-methyl-1-[[(2~{S})-1-[[(3~{S})-1-methylsulfanyl-4-oxidanylidene-pentan-3-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-butan-2-yl]carbamate

ChemComp-ZN:
Unknown entry

ChemComp-S7Q:
(phenylmethyl) ~{N}-[(2~{S})-3-methyl-1-[[(2~{R})-1-[[(3~{R})-1-methylsulfanyl-4-oxidanylidene-pentan-3-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-butan-2-yl]carbamate

ChemComp-HOH:
WATER

Source
  • human rhinovirus 2
KeywordsVIRAL PROTEIN / Chymotrypsin-like cysteine protease / rhinoviral 2A protease / zVAM.fmk

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