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TitleNMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands.
Journal, issue, pagesJ. Med. Chem., Vol. 64, Page 11229-11246, Year 2021
Publish dateMay 5, 2021 (structure data deposition date)
AuthorsBaggio, C. / Kulinich, A. / Dennys, C.N. / Rodrigo, R. / Meyer, K. / Ethell, I. / Pellecchia, M.
External linksJ. Med. Chem. / PubMed:34293864
MethodsX-ray diffraction
Resolution1.43 Å
Structure data

PDB-7ofv:
NMR-guided design of potent and selective EphA4 agonistic ligands
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSFERASE / EphA4 / 150D4 / ephrin / RTK

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