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TitleA Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress.
Journal, issue, pagesCancers (Basel), Vol. 13, Year 2021
Publish dateJul 28, 2020 (structure data deposition date)
AuthorsMoeglin, E. / Desplancq, D. / Stoessel, A. / Massute, C. / Ranniger, J. / McEwen, A.G. / Zeder-Lutz, G. / Oulad-Abdelghani, M. / Chiper, M. / Lafaye, P. ...Moeglin, E. / Desplancq, D. / Stoessel, A. / Massute, C. / Ranniger, J. / McEwen, A.G. / Zeder-Lutz, G. / Oulad-Abdelghani, M. / Chiper, M. / Lafaye, P. / Di Ventura, B. / Didier, P. / Poterszman, A. / Weiss, E.
External linksCancers (Basel) / PubMed:34282773
MethodsX-ray diffraction
Resolution1.55 Å
Structure data

PDB-6zwk:
Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody)
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • vicugna pacos (alpaca)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / NANOBODY / PHOSPHOPEPTIDE-RECOGNITION PROTEIN / GAMMA-H2AX

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