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Structure paper

TitleStructure-guided microbial targeting of antistaphylococcal prodrugs.
Journal, issue, pagesElife, Vol. 10, Year 2021
Publish dateDec 11, 2020 (structure data deposition date)
AuthorsMiller, J.J. / Shah, I.T. / Hatten, J. / Barekatain, Y. / Mueller, E.A. / Moustafa, A.M. / Edwards, R.L. / Dowd, C.S. / Planet, P.J. / Muller, F.L. ...Miller, J.J. / Shah, I.T. / Hatten, J. / Barekatain, Y. / Mueller, E.A. / Moustafa, A.M. / Edwards, R.L. / Dowd, C.S. / Planet, P.J. / Muller, F.L. / Jez, J.M. / Odom John, A.R.
External linksElife / PubMed:34279224
MethodsX-ray diffraction
Resolution1.6 - 1.65 Å
Structure data

PDB-7l0a:
Crystal structure of s-formylglutathione hydrolase (FrmB) from Staphylococcus aureus, apoenzyme
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-7l0b:
Crystal structure of hydroxyacyl glutathione hydrolase (GloB) from Staphylococcus aureus, apoenzyme
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • staphylococcus aureus (bacteria)
KeywordsHYDROLASE / FrmB / GloB / esterase

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