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TitleStructural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22.
Journal, issue, pagesJ. Biol. Chem., Vol. 297, Page 100966-100966, Year 2021
Publish dateApr 7, 2021 (structure data deposition date)
AuthorsEreno-Orbea, J. / Liu, X. / Sicard, T. / Kucharska, I. / Li, W. / Borovsky, D. / Cui, H. / Feng, Y. / Dimitrov, D.S. / Julien, J.P.
External linksJ. Biol. Chem. / PubMed:34273351
MethodsX-ray diffraction
Resolution1.6 - 2.41 Å
Structure data

PDB-7o4y:
m971 Fab in complex with anti-Kappa VHH domain
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-7o52:
CD22 d6-d7 in complex with Fab m971
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • lama glama (llama)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fab / CD22

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