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TitleProtective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch.
Journal, issue, pagesNat. Immunol., Vol. 22, Page 958-968, Year 2021
Publish dateMar 23, 2020 (structure data deposition date)
AuthorsDai, L. / Xu, K. / Li, J. / Huang, Q. / Song, J. / Han, Y. / Zheng, T. / Gao, P. / Lu, X. / Yang, H. ...Dai, L. / Xu, K. / Li, J. / Huang, Q. / Song, J. / Han, Y. / Zheng, T. / Gao, P. / Lu, X. / Yang, H. / Liu, K. / Xia, Q. / Wang, Q. / Chai, Y. / Qi, J. / Yan, J. / Gao, G.F.
External linksNat. Immunol. / PubMed:34267374
MethodsX-ray diffraction
Resolution2.99 - 3.1 Å
Structure data

PDB-7bpk:
Zika virus envelope protein mutant bound to mAb
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-7bq5:
ZIKV sE bound to mAb Z6
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

Source
  • zika virus
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Zika virus / envelop protein / monoclonal antibody / VIRAL PROTEIN / VIRAL PROTEIN-IMMUNE SYSTEM complex / antibody / fusion loop

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