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Title | Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 9960-9988, Year 2021 |
Publish date | Dec 8, 2019 (structure data deposition date) |
Authors | Campiani, G. / Cavella, C. / Osko, J.D. / Brindisi, M. / Relitti, N. / Brogi, S. / Saraswati, A.P. / Federico, S. / Chemi, G. / Maramai, S. ...Campiani, G. / Cavella, C. / Osko, J.D. / Brindisi, M. / Relitti, N. / Brogi, S. / Saraswati, A.P. / Federico, S. / Chemi, G. / Maramai, S. / Carullo, G. / Jaeger, B. / Carleo, A. / Benedetti, R. / Sarno, F. / Lamponi, S. / Rottoli, P. / Bargagli, E. / Bertucci, C. / Tedesco, D. / Herp, D. / Senger, J. / Ruberti, G. / Saccoccia, F. / Saponara, S. / Gorelli, B. / Valoti, M. / Kennedy, B. / Sundaramurthi, H. / Butini, S. / Jung, M. / Roach, K.M. / Altucci, L. / Bradding, P. / Christianson, D.W. / Gemma, S. / Prasse, A. |
External links | J. Med. Chem. / PubMed:34251197 |
Methods | X-ray diffraction |
Resolution | 2.03951514036 Å |
Structure data | PDB-6v79: |
Chemicals | ChemComp-ZN: ChemComp-K: ChemComp-QQD: ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / Histone Deacetylase |