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TitleDiscovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display.
Journal, issue, pagesAcs Cent. Sci., Vol. 7, Page 1001-1008, Year 2021
Publish dateDec 21, 2020 (structure data deposition date)
AuthorsNorman, A. / Franck, C. / Christie, M. / Hawkins, P.M.E. / Patel, K. / Ashhurst, A.S. / Aggarwal, A. / Low, J.K.K. / Siddiquee, R. / Ashley, C.L. ...Norman, A. / Franck, C. / Christie, M. / Hawkins, P.M.E. / Patel, K. / Ashhurst, A.S. / Aggarwal, A. / Low, J.K.K. / Siddiquee, R. / Ashley, C.L. / Steain, M. / Triccas, J.A. / Turville, S. / Mackay, J.P. / Passioura, T. / Payne, R.J.
External linksAcs Cent. Sci. / PubMed:34230894
MethodsX-ray diffraction
Resolution3.96 Å
Structure data

PDB-7l4z:
Structure of SARS-CoV-2 spike RBD in complex with cyclic peptide
Method: X-RAY DIFFRACTION / Resolution: 3.96 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • severe acute respiratory syndrome coronavirus 2
  • synthetic construct (others)
KeywordsVIRAL PROTEIN / COVID-19 / spike / RBD / cyclic peptide

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