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TitleThe MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling.
Journal, issue, pagesCell Death Dis, Vol. 12, Page 638-638, Year 2021
Publish dateDec 18, 2019 (structure data deposition date)
AuthorsZhang, Y. / Liu, J. / Yu, D. / Zhu, X. / Liu, X. / Liao, J. / Li, S. / Wang, H.
External linksCell Death Dis / PubMed:34158471
MethodsX-ray diffraction
Resolution2.41 - 2.5 Å
Structure data

PDB-6lk5:
MLKL mutant - T357ES358D
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6lk6:
MLKL mutant - T357AS358A
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Protein Phosphorylation

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