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TitleThe Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between beta 2 -Microglobulin and H Chain Conserved in Evolution.
Journal, issue, pagesJ Immunol., Year 2021
Publish dateJan 30, 2020 (structure data deposition date)
AuthorsWu, Y. / Zhang, N. / Wei, X. / Lu, S. / Li, S. / Hashimoto, K. / Dijkstra, J.M. / Xia, C.
External linksJ Immunol. / PubMed:34145057
MethodsX-ray diffraction
Resolution2.302 Å
Structure data

PDB-6luo:
Structure of nurse shark beta-2-microglobulin
Method: X-RAY DIFFRACTION / Resolution: 2.302 Å

PDB-6lup:
Crystal structure of shark MHC CLASS I for 2.3 angstrom
Method: X-RAY DIFFRACTION / Resolution: 2.302 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • ginglymostoma cirratum (nurse shark)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / nurse shark / monomer beta-2-microglobulin / MHC class I / MHC / SHARK / ADAPTIVE IMMUNE / PROTEIN BINDING-IMMUNE SYSTEM complex

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