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Structure paper

TitleTwo human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.
Journal, issue, pagesPlos Pathog., Vol. 17, Page e1009655-e1009655, Year 2021
Publish dateOct 9, 2020 (structure data deposition date)
AuthorsSands, N.A. / Beernink, P.T.
External linksPlos Pathog. / PubMed:34125873
MethodsX-ray diffraction
Resolution1.5 - 2 Å
Structure data

PDB-7ke1:
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-7ket:
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-7lcv:
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

ChemComp-LI:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • neisseria meningitidis (bacteria)
KeywordsIMMUNE SYSTEM / human / antibody / Fab / meningococcal vaccine / Factor H binding protein / complex

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