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TitleActivation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition.
Journal, issue, pagesNat Commun, Vol. 12, Page 3479-3479, Year 2021
Publish dateSep 17, 2020 (structure data deposition date)
AuthorsObaji, E. / Maksimainen, M.M. / Galera-Prat, A. / Lehtio, L.
External linksNat Commun / PubMed:34108479
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-7aeo:
Human ARTD2 in complex with DNA oligonucleotides
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / ARTD2 / PARP2 / DNA-damage / DNA-repair / ADP-ribosylation / DNA-binding protein

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