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-Structure paper
Title | Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion. |
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Journal, issue, pages | Chem Sci, Vol. 11, Page 10792-10801, Year 2020 |
Publish date | Feb 27, 2020 (structure data deposition date) |
Authors | Kidd, S.L. / Fowler, E. / Reinhardt, T. / Compton, T. / Mateu, N. / Newman, H. / Bellini, D. / Talon, R. / McLoughlin, J. / Krojer, T. ...Kidd, S.L. / Fowler, E. / Reinhardt, T. / Compton, T. / Mateu, N. / Newman, H. / Bellini, D. / Talon, R. / McLoughlin, J. / Krojer, T. / Aimon, A. / Bradley, A. / Fairhead, M. / Brear, P. / Diaz-Saez, L. / McAuley, K. / Sore, H.F. / Madin, A. / O'Donovan, D.H. / Huber, K.V.M. / Hyvonen, M. / von Delft, F. / Dowson, C.G. / Spring, D.R. |
External links | Chem Sci / PubMed:34094333 |
Methods | X-ray diffraction |
Resolution | 1.7 Å |
Structure data | PDB-6y6z: |
Chemicals | ChemComp-OEE: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / PBP3 / Penicillin Binding Proteins / Peptidoglycan production / transpeptidation |