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TitleNAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 118, Year 2021
Publish dateJul 20, 2020 (structure data deposition date)
AuthorsDiwo, M. / Michel, W. / Aurass, P. / Kuhle-Keindorf, K. / Pippel, J. / Krausze, J. / Wamp, S. / Lang, C. / Blankenfeldt, W. / Flieger, A.
External linksProc. Natl. Acad. Sci. USA / PubMed:34074754
MethodsX-ray diffraction
Resolution1.81 - 2.3 Å
Structure data

PDB-6zth:
Phospholipase PlaB from Legionella pneumophila
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6zti:
Phospholipase PlaB from Legionella pneumophila in complex with thio-NAD
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-HOH:
WATER

ChemComp-SND:
THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE

ChemComp-GOL:
GLYCEROL

Source
  • legionella pneumophila (bacteria)
KeywordsHYDROLASE / phospholipase / alpha/beta hydrolase / virulence / infectious disease

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