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Structure paper

TitleMicrobially Guided Discovery and Biosynthesis of Biologically Active Natural Products.
Journal, issue, pagesAcs Synth Biol, Vol. 10, Page 1505-1519, Year 2021
Publish dateMar 8, 2020 (structure data deposition date)
AuthorsSarkar, A. / Kim, E.Y. / Jang, T. / Hongdusit, A. / Kim, H. / Choi, J.M. / Fox, J.M.
External linksAcs Synth Biol / PubMed:33988973
MethodsX-ray diffraction
Resolution1.94 - 2.1 Å
Structure data

PDB-6w30:
Protein Tyrosine Phosphatase 1B Bound to Amorphadiene
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-7lfo:
Protein Tyrosine Phosphatase 1B
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SJA:
Amorphadiene

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PTP1B / Allosteric Inhibitor / Terpenoid

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