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-Structure paper
Title | Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 5645-5653, Year 2021 |
Publish date | Oct 20, 2020 (structure data deposition date) |
![]() | Stanford, S.M. / Diaz, M.A. / Ardecky, R.J. / Zou, J. / Roosild, T. / Holmes, Z.J. / Nguyen, T.P. / Hedrick, M.P. / Rodiles, S. / Guan, A. ...Stanford, S.M. / Diaz, M.A. / Ardecky, R.J. / Zou, J. / Roosild, T. / Holmes, Z.J. / Nguyen, T.P. / Hedrick, M.P. / Rodiles, S. / Guan, A. / Grotegut, S. / Santelli, E. / Chung, T.D.Y. / Jackson, M.R. / Bottini, N. / Pinkerton, A.B. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.3 Å |
Structure data | ![]() PDB-7kh8: |
Chemicals | ![]() ChemComp-WE7: ![]() ChemComp-NO3: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / Protein Tyrosine Phosphatase / LMWPTP / Inhibitor / Complex / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex |