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TitleIdentification and mechanistic analysis of an inhibitor of the CorC Mg 2+ transporter.
Journal, issue, pagesIscience, Vol. 24, Page 102370-102370, Year 2021
Publish dateJun 25, 2020 (structure data deposition date)
AuthorsHuang, Y. / Mu, K. / Teng, X. / Zhao, Y. / Funato, Y. / Miki, H. / Zhu, W. / Xu, Z. / Hattori, M.
External linksIscience / PubMed:33912817
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-7cfk:
Structure of the CBS domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with the novel inhibitor IGN95a
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-FX6:
(2S)-2-[(6-azanyl-9H-purin-8-yl)sulfanyl]butanoic acid

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • thermus parvatiensis (bacteria)
KeywordsTRANSPORT PROTEIN / transporter

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