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TitleSelectivity and Targeting of G-Quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 60, Page 15340-15343, Year 2021
Publish dateJan 2, 2020 (structure data deposition date)
AuthorsZhu, B.C. / He, J. / Liu, W. / Xia, X.Y. / Liu, L.Y. / Liang, B.B. / Yao, H.G. / Liu, B. / Ji, L.N. / Mao, Z.W.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:33899272
MethodsNMR (solution)
Structure data

PDB-6lnz:
NMR solution structure of VEGF G-quadruplex bound a non-planar cyclometalated-carbene platinum(II) complex
Method: SOLUTION NMR

Chemicals

ChemComp-EL9:
cyclometalated-carbene platinum(II) complex

Source
  • homo sapiens (human)
KeywordsDNA / VEGF G-quadruplex / solution structure / DNA-ligand complex / platinum complex

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