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TitleStructural analysis of new compound heterozygous variants in PEPD gene identified in a patient with Prolidase Deficiency diagnosed by exome sequencing.
Journal, issue, pagesGenet Mol Biol, Vol. 44, Page e20200393-e20200393, Year 2021
Publish dateFeb 20, 2019 (structure data deposition date)
AuthorsLinhares, N.D. / Wilk, P. / Wator, E. / Tostes, M.A. / Weiss, M.S. / Pena, S.D.J.
External linksGenet Mol Biol / PubMed:33877262
MethodsX-ray diffraction
Resolution1.569 - 1.99 Å
Structure data

PDB-6qsb:
Crystal Structure of Arg470His mutant of Human Prolidase with Mn ions
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

PDB-6qsc:
Crystal Structure of Arg470His mutant of Human Prolidase with Mn ions and GlyPro ligand
Method: X-RAY DIFFRACTION / Resolution: 1.569 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-MH2:
MANGANESE ION, 1 HYDROXYL COORDINATED

ChemComp-GLY:
GLYCINE

ChemComp-PRO:
PROLINE

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Metal binding / dipeptidase / mutation

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