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TitleToward Chemical Validation of Leishmania infantum Ribose 5-Phosphate Isomerase as a Drug Target.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 65, Page e0189220-e0189220, Year 2021
Publish dateMar 9, 2018 (structure data deposition date)
AuthorsDickie, E.A. / Ronin, C. / Sa, M. / Ciesielski, F. / Trouche, N. / Tavares, J. / Santarem, N. / Major, L.L. / Pemberton, I.K. / MacDougall, J. ...Dickie, E.A. / Ronin, C. / Sa, M. / Ciesielski, F. / Trouche, N. / Tavares, J. / Santarem, N. / Major, L.L. / Pemberton, I.K. / MacDougall, J. / Smith, T.K. / Cordeiro-da-Silva, A. / Ciapetti, P.
External linksAntimicrob. Agents Chemother. / PubMed:33875438
MethodsX-ray diffraction
Resolution1.57 Å
Structure data

PDB-6fxw:
Structure of Leishmania infantum type B ribose 5-phosphate isomerase
Method: X-RAY DIFFRACTION / Resolution: 1.57 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • leishmania infantum (eukaryote)
KeywordsISOMERASE / PENTOSE PHOSPHATE PATHWAY TYPE B RIBOSE 5-PHOSPHATE ISOMERASE R5P

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