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-Structure paper
Title | Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule. |
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Journal, issue, pages | Chembiochem, Vol. 22, Page 2107-2110, Year 2021 |
Publish date | Jan 5, 2021 (structure data deposition date) |
Authors | Wigle, T.J. / Ren, Y. / Molina, J.R. / Blackwell, D.J. / Schenkel, L.B. / Swinger, K.K. / Kuplast-Barr, K. / Majer, C.R. / Church, W.D. / Lu, A.Z. ...Wigle, T.J. / Ren, Y. / Molina, J.R. / Blackwell, D.J. / Schenkel, L.B. / Swinger, K.K. / Kuplast-Barr, K. / Majer, C.R. / Church, W.D. / Lu, A.Z. / Mo, J. / Abo, R. / Cheung, A. / Dorsey, B.W. / Niepel, M. / Perl, N.R. / Vasbinder, M.M. / Keilhack, H. / Kuntz, K.W. |
External links | Chembiochem / PubMed:33838082 |
Methods | X-ray diffraction |
Resolution | 2.25 - 2.57 Å |
Structure data | PDB-7l9y: PDB-7lun: |
Chemicals | ChemComp-XRM: ChemComp-CL: ChemComp-EDO: ChemComp-HOH: ChemComp-YFG: ChemComp-GOL: |
Source |
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Keywords | TRANSFERASE/Inhibitor / PARP14 / ARTD8 / monoPARP / ADP ribosylation / inhibitor complex / TRANSFERASE-Inhibitor complex / TRANSFERASE |